Johan W Mouton Selected Research

Ceftazidime (Fortum)

9/2016	Modelling concentrations of antimicrobial drugs: comparative pharmacokinetics of cephalosporin antimicrobials and accuracy of allometric scaling in food-producing and companion animals.
1/2016	Pharmacodynamics of Ceftazidime and Avibactam in Neutropenic Mice with Thigh or Lung Infection.
4/2015	Pharmacokinetics and penetration of ceftazidime and avibactam into epithelial lining fluid in thigh- and lung-infected mice.
4/2013	Optimal exposures of ceftazidime predict the probability of microbiological and clinical outcome in the treatment of nosocomial pneumonia.
1/2013	The therapeutic effect of tigecycline, unlike that of Ceftazidime, is not influenced by whether the Klebsiella pneumoniae strain produces extended-spectrum β-lactamases in experimental pneumonia in rats.
5/2007	Continuous administration of PBP-2- and PBP-3-specific beta-lactams causes higher cytokine responses in murine Pseudomonas aeruginosa and Escherichia coli sepsis.
9/2006	Effect of treatment duration on pharmacokinetic/pharmacodynamic indices correlating with therapeutic efficacy of ceftazidime in experimental Klebsiella pneumoniae lung infection.
6/2005	A retrospective analysis using Monte Carlo simulation to evaluate recommended ceftazidime dosing regimens in healthy volunteers, patients with cystic fibrosis, and patients in the intensive care unit.

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Johan W Mouton Research Topics

Disease

69	Infections 04/2022 - 08/2002
24	Aspergillosis 01/2019 - 12/2008
15	Urinary Tract Infections (Urinary Tract Infection) 11/2021 - 09/2015
15	Body Weight (Weight, Body) 01/2020 - 06/2002
8	Pneumonia (Pneumonitis) 01/2018 - 08/2002
7	Cystic Fibrosis (Mucoviscidosis) 12/2017 - 02/2003
5	Abscess 01/2020 - 12/2002
4	Communicable Diseases (Infectious Diseases) 04/2022 - 10/2013
4	Critical Illness (Critically Ill) 01/2020 - 09/2013
4	Sepsis (Septicemia) 10/2019 - 08/2002
4	Healthcare-Associated Pneumonia 01/2018 - 02/2008
3	Candidiasis (Moniliasis) 01/2021 - 10/2007
3	Renal Insufficiency (Renal Failure) 01/2019 - 01/2004
3	Lung Diseases (Lung Disease) 01/2016 - 09/2012
3	Coinfection 10/2007 - 12/2002
2	Morbid Obesity 10/2019 - 03/2014
2	Confusion (Bewilderment) 01/2019 - 02/2015
2	Cystitis 01/2019 - 01/2018
2	Surgical Wound Infection 05/2018 - 03/2014
2	Bacterial Infections (Bacterial Infection) 01/2018 - 01/2018
2	Ototoxicity 12/2015 - 01/2004
2	Invasive Pulmonary Aspergillosis 03/2015 - 05/2014
2	Mycoses (Diseases, Fungus) 01/2015 - 08/2008
2	Porcine Reproductive and Respiratory Syndrome (PRRS) 07/2014 - 12/2012
1	Invasive Candidiasis 01/2021
1	Peritonitis 01/2020
1	Obesity 01/2020
1	Gram-Negative Bacterial Infections 01/2019
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2018
1	Abdominal Abscess 05/2018
1	Appendicitis 05/2018
1	Ventilator-Associated Pneumonia 01/2018
1	Diarrhea 01/2018
1	Nausea 01/2018
1	Dysuria 01/2018

Drug/Important Bio-Agent (IBA)

27	Anti-Bacterial Agents (Antibiotics)IBA 04/2022 - 12/2002
19	Pharmaceutical PreparationsIBA 10/2021 - 06/2002
15	AzolesIBA 01/2019 - 06/2002
14	Voriconazole (Vfend)FDA LinkGeneric 06/2017 - 08/2008
12	Fosfomycin FDA Link 11/2021 - 09/2017
10	Colistin (Coly-Mycin)FDA Link 12/2020 - 02/2015
9	Carbapenems (Carbapenem Antibiotics)IBA 04/2022 - 03/2015
8	posaconazole FDA Link 03/2021 - 02/2010
8	Nitrofurantoin (Macrodantin)FDA LinkGeneric 09/2019 - 09/2015
8	Ceftazidime (Fortum)FDA LinkGeneric 09/2016 - 06/2005
7	Meropenem (Merrem)FDA LinkGeneric 12/2020 - 05/2007
5	isavuconazoleIBA 01/2018 - 09/2011
4	TriazolesIBA 01/2018 - 08/2008
4	Anidulafungin FDA Link 11/2016 - 01/2013
3	Polymyxins (Polymyxin)IBA 09/2020 - 02/2015
3	Vancomycin FDA LinkGeneric 01/2020 - 01/2004
3	Gentamicins (Gentamicin)FDA LinkGeneric 10/2019 - 07/2015
3	liposomal amphotericin B FDA Link 01/2019 - 04/2013
3	carbapenemaseIBA 01/2019 - 01/2017
3	Antifungal AgentsIBA 12/2017 - 10/2011
3	ProdrugsIBA 12/2017 - 01/2015
3	Tobramycin (Nebcin)FDA LinkGeneric 12/2017 - 06/2005
3	Tigecycline (Tygacil)FDA Link 01/2017 - 01/2013
3	Amoxicillin (Wymox)FDA LinkGeneric 04/2009 - 01/2008
2	LactamsIBA 04/2022 - 10/2021
2	ceftazidime drug combination avibactamIBA 10/2021 - 01/2016
2	Fluconazole (Zonal)FDA LinkGeneric 01/2021 - 10/2007
2	Imipenem FDA Link 01/2020 - 12/2002
2	Imipenem Drug Combination Cilastatin (Primaxin)FDA Link 01/2020 - 02/2015
2	AminoglycosidesIBA 10/2019 - 05/2019
2	Polymyxin B (Aerosporin)FDA LinkGeneric 01/2019 - 02/2015
2	EchinocandinsIBA 01/2018 - 10/2013
2	Amikacin (A.M.K)FDA LinkGeneric 10/2016 - 12/2015
2	avibactamIBA 01/2016 - 04/2015
2	Tazobactam FDA LinkGeneric 08/2015 - 05/2004
2	temocillinIBA 03/2015 - 02/2008
2	Ciprofloxacin (Cipro)FDA LinkGeneric 10/2014 - 08/2002
2	Pattern Recognition ReceptorsIBA 07/2014 - 12/2012
2	Amphotericin B (Amphotericin)FDA LinkGeneric 10/2013 - 06/2002
2	Therapeutic UsesIBA 01/2013 - 09/2006
2	Ceftizoxime (Cefizox)FDA Link 10/2007 - 05/2004
2	beta-LactamsIBA 05/2007 - 09/2006
2	Piperacillin FDA LinkGeneric 05/2004 - 02/2003
2	Itraconazole (Sporanox)FDA LinkGeneric 04/2004 - 06/2002
1	TabletsIBA 01/2021
1	Cefpirome (HR 810)IBA 04/2020
1	Polypropylenes (Polypropylene)IBA 01/2020
1	ZincIBA 01/2020
1	Tromethamine (Trometamol)FDA Link 01/2020
1	CollagenIBA 01/2020
1	omadacyclineIBA 10/2019
1	nitroxolineIBA 11/2018
1	NitritesIBA 01/2018
1	Oxygen (Dioxygen)IBA 01/2018
1	leukocyte esteraseIBA 01/2018

Therapy/Procedure

30	Therapeutics 01/2021 - 06/2002
3	Critical Care (Surgical Intensive Care) 04/2022 - 02/2008
2	Bariatric Surgery 01/2020 - 10/2019
2	Punctures 01/2020 - 12/2002
2	Salvage Therapy 01/2019 - 10/2013
1	Ligation 01/2020
1	Respiratory Therapy (Therapy, Respiratory) 01/2019
1	Antibiotic Prophylaxis 05/2018
1	Appendectomy 05/2018
1	Intravenous Administration 05/2018